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RestEaze by Tanzen Medical
Leg Movement and Arousal Analytics, Night After Night at Home
RestEaze is a multi-night, ambulatory monitoring platform designed to assist clinicians in diagnosing and managing RLS and PLMD. A standalone variant, RestEaze Guardian, developed with funding from the Defense Health Agency, runs its analytics on the device, offline, to monitor sleep and predict next-day performance.
Cortical Arousal DetectionLMS & PLMS CharacterizationAutonomic Arousal Detection
Advanced LMS Characterization
A New Approach to Leg Movements During Sleep
Beyond the single-night lab study: continuous, high-fidelity leg movement recording, night after night.
The Problem:Leg movements during sleep are usually measured with surface EMG during an overnight lab study: accurate, but limited to a single night in an unfamiliar bed. Monitoring LMS and PLMS over time needs something comfortable and affordable enough to wear at home.
Fig. 1 — RestEaze band, exploded, skin side up
1PPG Optical SensorSensor face
Shines light into the skin and reads what comes back to follow capillary blood flow, giving heart rate, heart-rate variability and respiratory rate through the night.
1. Multi-Sensor Approach
Five sensors in one ankle band record all night, starting as soon as the band is on: motion for leg movements and position, PPG for heart rate, HRV and respiration, plus skin conductance and temperature.
2. Every Leg Movement, Counted
Each leg movement is detected and counted, then scored by standard rules: during sleep or the whole night, isolated or periodic, with or without a cortical arousal (found by machine learning). Counts become per-hour indices, like the PLMS index.
3. Advanced Analytics
Each night is scored by morning and ready in the dashboard, with trends across nights:
- Sleep
- Total sleep time, efficiency, WASO, sleep quality, in-bed times
- Movements
- LM, PLM, LMS and PLMS counts and indices, with arousal
- Vitals
- Heart rate, HRV and respiration through the night
- Timeline
- RESTful, restless and wake, minute by minute
System Architecture
How RestEaze Works: Band, App and Cloud
Three parts, one data path: the band records each night, the app syncs it, and the cloud scores it for your dashboard.
01
The Band
Starts on its own: in automatic recording mode, recording begins when the band is placed on the skin.
Stores or streams: the night is recorded to the band's memory, or streamed live to the app.
One band or a pair: mirrored left and right bands, work with the sensors work on the inside of the ankle
Bluetooth
02
The App
Study / Subject IDDEMO-014
LLeft LegConnected (ready)
RRight LegConnected (ready)
Device status: connection and battery level for each band, left and right.
Digital sleep diary: morning and evening entries, paired with the night's sensor record.
Sync and upload: after recording, the night downloads from the band and uploads to the cloud.
Upload
03
The Cloud
Demo dataSE SQ TST TRT WASO PLMS PLMSI PLMSA PLMSAI
Sleep Quality
65.8%
6.8h
490min
40min
Periodic Leg Movements During Sleep
121
17.8/hr
18
2.6/hr
Automated analytics: each night is scored once it's uploaded: leg movements, arousals, sleep and vital signs.
Clinician dashboard: nightly and multi-night views, studies and subjects, and cohort statistics.
Data access: export scored results, reports, and raw sensor data based on user permission.
Advanced Features
Comprehensive Sleep Monitoring
RestEaze pairs purpose-built sensors with AASM-based scoring for a detailed picture of every night.
Leg Movement Detection
Signal processing and machine learning label each leg movement during sleep (LMS), find the periodic series (PLMS) and flag the movements that come with cortical arousals.
Periodic Leg Movements During Sleep
121
17.8/hr
18
2.6/hr
Multi-Night Recording
Night-to-night variability is a problem for single-night lab studies. RestEaze is designed for multi-night recording, so a screening doesn't hinge on one night.
7-Night Averages
17.5/hr
16.0/hr
Bilateral Recording
Research and clinical accuracy are at the core of our products. Record from one leg or both, with the two bands kept on a shared clock.
- Unilateral or bilateral protocols
- Millisecond multi-device synchronization
- Left/right movement attribution
Digital Sleep Diary
Patients log subjective sleep measures in the app each morning and evening, paired automatically with the night's objective sensor record.
- Guided morning and evening entries
- Bedtime, wake time and symptom logs
- Paired with the matching night of data
Physician Dashboard
Clinicians create patient accounts and review each night's processed data in the RestEaze dashboard.
- Patient and cohort account management
- Night-by-night PLM and arousal review
- Data export, with PDF reports coming soon
Clinical Sleep Metrics
What RestEaze Measures, Night by Night
Leg movements, arousals, sleep timing and vital signs, scored for every night recorded.
01
Isolated and Periodic Leg Movement
Each movement's onset and duration, with counts and per-hour indices for the whole recording and during sleep only.
02
Leg Movements With Arousal
Whether each leg movement is associated with a cortical arousal, with counts and per-hour indices of those movements.
03
Physiological Data
Heart rate, heart-rate variability, respiratory rate and skin temperature.
04
In-Bed Times
In-bed and out-of-bed times, from whether the leg is upright or lying.
05
Sleep Times and Awakenings
Sleep onset and offset; time, duration and count of awakenings.
06
Sleep Quality Metrics
Sleep efficiency (SE) and total sleep time (TST).
Bring RestEaze™ to Your Clinic or Study
Talk with our team about how multi-night, at-home leg movement monitoring can support your diagnoses, treatment tracking and trial endpoints.